PIPAC - Titelbild


The „Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)“ for the abdominal cavity and its sister method for the chest cavity (PITAC)

A great deal of patients who do not effectively respond to conventional systemic chemotherapy and do not meet the criteria for cytoreductive surgery and HIPEC, however, are likely to benefit from the Pressurized Aerosol Intraperitoneally Chemotherapy ( PIPAC ) in the abdomen and chest (PITAC). Currently these patients of peritoneal cancer, including many young patients, hardly can be treated in an effective manner.

On the basis of the Pressurized Aerosol Intraperitoneally Chemotherapy (PIPAC) we have developed another method of treatment in which chemotherapy during a laparoscopy (keyhole surgery) is applied under compression in aerosol form. This therapy is very well  tolerated by the patients. Analyzes have shown significant pharmacological advantages, both to the systemic chemotherapy as well as to the HIPEC. Moreover, first treatments on humans have shown promising results.

The pressure aerosol chemotherapy (Pressurized Intraperitoneally Aerosol Chemotherapy, PIPAC) is an innovative method of the intraperitoneal chemotherapy for peritoneal cancer (peritoneal). Its basic principle was first published in the year 2000 and its first use in humans was carried out in late 2011 at the Evangelical Hospital Bielefeld by Prof. Reymond. Due to the better utilization of physical properties (application of pressure, gas form) the PIPAC is capable to administer medication in body cavities of humans (such as for example in the abdomen or chest) in a particularly effective manner. Therefore only 10 percent of the systemic chemotherapy dose are needed. During the PIPAC only medications are used, whose effectiveness in a particular tumor type has been proven ulterior.




Current reports

Newspaper report of the Schwarzwälder Bote - "Strohhalm" macht Patientin glücklich

Workshop on Management of Peritoneal Surface Malignancy, Irkutsk, Russland

PIPAC Symposium & Live Demonstration, Mumbai, Indien

1st Asia-Pacific PIPAC Symposium & Hands-on Course, Singapore



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